Improving the knowledge of dealing with crises that threaten human life can ensure the resilience of the human generation. The continued spread of the covid-19 virus has affected Iran's national health systems as well as other health systems around the world. The covid-19 pandemic created a form of socio-economic and especially spatial inequality and ultimately health inequality. The public health system of Khoy cities in West Azerbaijan province was also affected by the spread of this virus and reported its first case of infection and death on April 30, 2019, and recorded 530 deaths. Today he is fighting this virus. Using the descriptive-analytical method, this research studied the spatial distribution of the covid-19 virus in 62 neighborhoods of city Khoy from the beginning of 2019 to the end of 2012 using geographic information system. The purpose of this research is to use geographic measurement methods to analyze the spatial distribution of the Covid-19 virus based on the spatial diffusion theory. The findings of the research showed that the range of distribution is concentrated in the western neighborhoods of Khoy city with high population density and the oval elongation of the distribution with a relative north-south direction, and unequal factors are effective and evident in enjoying stable health. The mechanism of the spatial spread of the Covid-19 virus in Khoy areas is relatively compatible with some of the steps and the mechanism of the spatial spread theory, and some of the steps are generally disused in this field.