The corona virus pandemic has disrupted the daily life of people all over the world and therefore it is necessary to address this health issue and examine it in terms of geographical features. The main goal of this research is to investigate the spatial distribution of corona disease in Ardabil city. The type of research based on the purpose is applied and descriptive-analytical in terms of its nature and method. To analyze the results, spatial statistics methods have been used in the Arc GIS software environment. The method of collecting information is a library, and the statistical population of the research is the patients with corona disease in Ardabil city in 2020. In the analysis of the spatial distribution pattern, the techniques of central average and standard deviation curve, nearest neighbor index , and hot spot analysis have been used. Based on the findings of the research and the output of the standard deviation curve of the distribution of the disease, it is concentrated in the northeastern direction of the city, and based on the analysis of the nearest neighborhood, the corona disease has spread in the form of a cluster in the city of Ardabil.