The present study aimed to investigate the resilience and business life cycle of rural women-owned enterprises in Pasargad County. The statistical population consisted of women engaged in microenterprises and home-based businesses who were members of microcredit funds. In terms of purpose, this research was applied, and it was conducted using a descriptive–analytical approach. Data were collected through a survey using questionnaires administered to 103 rural women. Data analysis was performed using Structural Equation Modeling (SEM) and AMOS24 software. The findings revealed that, in Pasargad County, given the diversity of economic activities, a combination of structural and individual factors simultaneously affects both the business life cycle and business resilience. Regarding the business life cycle, the results indicated that supportive policies, creativity, business environment, and managerial skills had positive and significant effects, whereas self-confidence demonstrated a negative effect. This finding suggests that women with higher levels of self-confidence may exhibit less inclination toward collective learning or consultation with supporting institutions, thereby distancing themselves from support systems and knowledge networks. In contrast, creativity and a favorable business environment played an active role in enhancing the business life cycle. Creativity, particularly in handicrafts and food-processing sectors, served as a source of innovation and product differentiation, helping businesses move beyond the start-up stage toward growth. In addition, creativity and the influence of social networks played complementary roles in sustaining the economic and social viability of businesses. Therefore, in Pasargad County, economic resilience emerges from the interaction between individual capacities (such as creativity and behavioral control) and environmental capacities (such as the business environment and social network influence). Due to the relatively dynamic and diverse economic environment of the county, supportive policies appear to play a more indirect role.