In today’s world, women’s economic empowerment is not merely a human right but also a strategic imperative for sustainable development. In the knowledge-based economy, the gender digital divide has emerged as a major obstacle to achieving the Sustainable Development Goals (SDGs). Given the pivotal role women play in Iran’s economy and social structure, their digital empowerment can be a powerful driver of regional sustainable development. This study aims to systematically review the literature and analyze available documents on the relationship between women’s digital empowerment and the economic, social, and environmental dimensions of sustainable development across different regions of Iran. Using a library-based research approach, the study analyzes documents, reports issued by development organizations, and scholarly articles published over the past decade. The findings of this review indicate that women’s access to digital infrastructure, media literacy, and online entrepreneurship skills is directly associated with higher household incomes, poverty reduction in disadvantaged regions, and greater social equity. However, challenges such as cultural barriers, inadequate infrastructure in remote areas, and gaps in practical skills have hindered the full realization of this potential. The study therefore recommends that national policies aimed at achieving regional sustainable development prioritize gender digital equity and provide digital skills training tailored to the local needs of different regions.