Strengthening mid-sized cities is one of the strategies considered in the integration of the settlement system and regional development, and developing cultural infrastructure in these cities is one of their first developments, because it can contribute significantly to improving the quality of life, increasing competitiveness, and urban creativity. The aim of this study is to evaluate and rank the middle cities of Iran in terms of cultural infrastructure. The statistical population of this study is cities with a population range of 100,000 to 250,000 according to the 2016 census, which is 67 cities. Since the criteria and indicators under study do not have the same importance, their weights were calculated using the CRITIC weighting method before ranking the cities. Weights were calculated at two levels: indicators and criteria. The weighting results showed that the cultural center criterion with a weight of 0.299 and then the public library with a weight of 0.263 are the most important criteria, and the theatre hall and cinema criteria are in the next position with a weight of 0.242 and 0.196, respectively. The COPRAS method was used to rank cities in terms of access to the four infrastructures under study. The results of this method showed that the three cities of Bushehr, Shushtar, and Behbahan ranked first to third. In addition to ranking, according to the value of N, cities were classified into 5 levels with 20-point intervals. The first level includes cities with a score of (80 Nj> ≤100), which includes the three cities mentioned above. 5 cities (46.7 ℅) are in the second level (60 Nj> ≤80), 15 cities (39.22 ℅) are in the third level (40 Nj> ≤60), 36 cities (73.53 ℅) are in the fourth level (20 N_j> ≤40), and 8 cities (94.11 ℅) are in the fifth level (20 N_j≤).